mouse skeletal muscle cell line c2cl2 (ATCC)
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mouse skeletal muscle cell line c2cl2
Mouse Skeletal Muscle Cell Line C2cl2, supplied by ATCC, used in various techniques. Bioz Stars score: 95/100, based on 219 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/c2cl2+cells/Primary+Skeletal+Muscle+Cells/pm37972244-42-12-21
Average 95 stars, based on 219 article reviews
Mouse Skeletal Muscle Cell Line C2cl2, supplied by ATCC, used in various techniques. Bioz Stars score: 95/100, based on 219 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/c2cl2+cells/Primary+Skeletal+Muscle+Cells/pm37972244-42-12-21
Average 95 stars, based on 219 article reviews
mouse skeletal muscle cell line c2cl2 - by Bioz Stars,
2026-09
95/100 stars
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Modification:Article Title: Anti-diabetic and anti-adipogenic effects of a novel selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor, 2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone (KR-66344). Article Snippet: The selective inhibitors of 11b-hydroxysteroid dehydrogenase type 1 (11b-HSD1) have considerable potential for treating type 2 diabetes mellitus and metabolic syndrome.. In the present study, we investigated the anti-diabetic and anti-adipogenic effects of 2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H1,2-benzothiazine-2-yl-1-phenylethanone (KR-66344), as a 11b-HSD1 inhibitor; we also investigated the underlying molecular mechanisms in the cortisone-induced 3T3-L1 adipogenesis model system and C57BL/6-Lep mice.. KR-66344 concentration-dependently inhibited 11b-HSD1 activity in human liver microsome, mouse C2C12 myotube and human SW982 cells. Article Title: Phosphatase and tensin homolog deleted on chromosome 10 suppression is an important process in peroxisome proliferator-activated receptor-gamma signaling in adipocytes and myotubes. Article Snippet: Peroxisome proliferator-activated receptor(PPAR ) activation enhances insulin sensitivity in type 2 diabetes mellitus.. However, downstream mediators of PPAR activation in adipocytes and myotubes, the most important cell types involved in glucose homeostasis, remained unclear.. Here we show by using two synthetic PPAR agonists (rosiglitazone and KR62776, a novel PPAR agonist) that phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is a key downstream mediator of PPAR signaling. |